Exploring new perspectives to make extraordinary discoveries

At Montara, we’re developing safer, more efficacious therapies to improve the lives of patients with neurological diseases.

Our mission is to develop innovative therapies for diseases of the brain by leveraging our proprietary platform to enhance drug safety and efficacy and enable the drugging of targets previously considered undruggable.

Introducing BrainOnly™, the uniquely versatile platform designed to prevent peripheral toxicities and concentrate neurological drugs’ activity in the brain, enhancing safety, increasing therapeutic index, and improving efficacy

Many promising drug candidates for neurological diseases fail to advance due to dose-limiting, off-tissue peripheral toxicities, which impede both safety and efficacy.

BrainOnly is a breakthrough platform that aims to prevent peripheral adverse events associated with neuroscience drugs. It holds the potential to deliver a new generation of brain-targeted therapeutics.

Access many currently undruggable targets and enhance the profile of existing drugs

Utilize with novel or existing small molecule inhibitors or activators

Broad applicability across neurological diseases, including neurodegenerative diseases and brain cancer

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Solid experience with a fresh perspective

Solid experience with a fresh perspective

We are Montara Therapeutics, a precision medicine neuroscience biotech startup based in San Francisco. Our experienced team has founded successful biotech companies, and we are supported by world-class scientific and chemistry advisory boards.

We present a new approach to tackling challenging established targets, along with unique experience in developing enzyme activators and domain expertise in mitophagy.

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We’re hiring. Find out more about joining the Montara team

Get in touch with Montara

Learn about opportunities with us, and sign up to receive news and updates.

We’re hiring.

Find out more about joining the Montara team.

Get in touch with Montara

Learn about opportunities with us, and sign up to receive news and updates.

We’re hiring.

Find out more about joining the Montara team.


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Get in touch with Montara

Learn about opportunities with us, and sign up to receive news and updates.


Message frequency may vary. You may opt out at any time. Privacy Policy and Terms of Use